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Medical Bioinformatics @Western
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papers
courses
faculty
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Events
Open House
17 Apr 2025 Research Opportunities in Bioinformatics, Biostatistics, AI and Data Science
Seminars
Talking to Cells, Tissues and Patient Data using Multimodal AI Agents
05 Nov 2026 Moritz Schaefer
Geometric Inference for Single-Cell and Spatial Omics
29 Oct 2026 Rong Ma
AI-Driven Design of Lipid Nanoparticles for mRNA Delivery
24 Sep 2026 Bowen Li
Beyond Prediction: From Generative Foundation Models to Medical World Models
08 Sep 2026 Youcheng Li
Act or Defer: Knowing When to Trust Medical Foundation Models with Guarantees
21 May 2026 Ying Jin
Leveraging large-scale genetic association studies to decipher causal mechanisms of Type 2 Diabetes
07 May 2026 Ozvan Bocher
Expectations and Insights from the Size of Phylogenetic Clades
24 Apr 2026 Ailene MacPherson
Mechanistic mathematical models to advance immunology
10 Apr 2026 Morgan Craig, PhD
Foundation models in pathology: The present and the future
23 Mar 2026 Andrew H. Song
Generative AI in Spatiotemporal Modeling of Cell Dynamics
12 Mar 2026 Siyu He
The Code of Survival: Machine Learning Deciphers How Life Thrives in Extreme Conditions
26 Feb 2026 Gurjit Randhawa
Can LLMs Achieve Causal Reasoning and Cooperation?
12 Feb 2026 Zhijing Jin
Publishing Functionally-Validated Sequence Variants at Scale in the ClinVar Database at the US National Institutes of Health: Our Experience
29 Jan 2026 Peter Rogan
Generative AI for Unlocking the Complexity of Cells
16 Jan 2026 Maria Brbic
Unsupervised Bayesian structural time series for estimation of disease variants from wastewater genome samples
11 Dec 2025 Devan Becker
From Models to Agents: Structuring Clinical AI through Reasoning, Generation, and Alignment
27 Nov 2025 Xiang Li, PhD
Multi-condition analysis of spatial omics data
13 Nov 2025 Mark D. Robinson
Sex Chromosome Aneuploidies in Humans and Cells: Origins, Consequences, and Insights from Global Biobank Meta-analyses
30 Oct 2025 Aoxing Liu, PhD
A generative deep learning approach to de novo antibiotic design
15 Oct 2025 Aarti Krishnan
The Virtual Lab of AI Designs New SARS-CoV-2 Nanobodies
25 Sep 2025 Kyle Swanson
Papers
CycleMix: Gaussian mixture modeling of the cell cycle.
Published 18 Aug 2026
Human mesenchymal stromal cell extracellular vesicles maintain therapeutic miRNA cargo despite exposure to cystic fibrosis bronchoalveolar lavage fluid.
Published 07 Aug 2026
Spatial transcriptomics supports a role for SOX4-driven signaling throughout the disease course of biliary atresia.
Published 28 Jul 2026
Selection profiles in RNA viruses reflect the characteristics of viruses more than individual proteins.
Published 24 Jul 2026
Pervasive HIV recombination limits the utility of circulating recombinant form nomenclature.
Published 13 Jul 2026
Deep Unsupervised Domain Adaptation for Translating Cancer Dependency Maps From Cell Lines to Breast Cancer Tumor Genomics.
Published 24 Jun 2026
Chromosomal and immune dysregulation underlying granular mitosis in glioblastoma.
Published 20 Jun 2026
Hac1-independent functions of Ire1 drive morphogenesis in Candida albicans through distinct transcriptional programs.
Published 17 Jun 2026
Heterozygous Nonsense Mutation in the Nuclear Transport Factor KPNA7, a Maternal Factor Active in Embryonic Tissues, Causes Autosomal Dominant Otosclerosis.
Published 12 Jun 2026
NOD2 activation reprograms infiltrating inflammatory monocytes in the Zika virus infected CNS to maintain neural correlates of learning and memory.
Published 04 Jun 2026
Mycobacteria Amplicon Sequencing Tool: automated resistance prediction and lineage classification for Mycobacterium tuberculosis.
Published 27 Apr 2026
Systemic and Local Adiposity in the Bone Marrow Microenvironment Associated With Improved Prognosis in Hodgkin Lymphoma: Imaging and Molecular Analysis.
Published 20 Apr 2026
PHYCUT: Scalable Multiplex CRISPR/Cas9 Editing for Genome Engineering in the Diatom Phaeodactylum tricornutum.
Published 14 Apr 2026
A copula-infused graph neural network for cell type classification in single-cell RNA sequencing data.
Published 06 Apr 2026
EpigeneticAgePipeline: An R Package for Comprehensive Assessment of Epigenetic Age Metrics From Methylation Microarrays.
Published 02 Apr 2026
Plant-based dietary patterns are associated with slower epigenetic aging.
Published 31 Mar 2026
Transcriptomic analysis of cells following decreased mitochondrial DNA-copy number reveals compensatory mechanisms in mitochondrial DNA replication and cellular energetics.
Published 28 Feb 2026
Better data for better predictions: data curation improves deep learning for sgRNA/Cas9 prediction.
Published 16 Feb 2026
Applications of AI to single-cell and spatial transcriptomics: current state-of-the-art and challenges.
Published 12 Feb 2026
Viral mimicry acts as a tumor suppressor in colitis.
Published 05 Feb 2026
Faculty
Tallulah Andrews
Assistant Professor
Integration of biological imaging and multiple -omics technologies to understand the structure of diseased tissues.
Pingzhao Hu
Associate Professor
Developing and applying computational and statistical techniques for integrative analysis of big multimodal health data for precision medicine.
Jennifer Guthrie
Assistant Professor
Combining bioinformatics, epidemiology, public health, genomics and microbiology to predict antimicrobial resistance, disease transmission and outbreaks.
Greg Gloor
Professor
Compositional data analysis and functional characterization of microbiomes.
Christina Castellani
Assistant Professor
Contribution of mitochondrial nuclear multiomic signalling to cardiovascular disease using bioinformatic approaches.
Art Poon
Professor
Development of computational methods to reconstruct the evolution and epidemiology of human RNA viruses.
Parisa Shooshtari
Assistant Professor
Developing computational, statistical and machine learning methods to understand cellular and molecular mechanisms underlying complex diseases.
Mike Hallett
Professor
Computational biology and bioinformatic approaches to biomarkers based on multi-variate, multi-modal gene signatures, especially in the context of cancer.
Vanessa Dumeaux
Assistant Professor
Genomics and computational approaches to understand the molecular aspects of human physiology and disease incidence/prognosis in the context of the individual (e.g. immune response, microbiome).